Pluristem Life Systems, Inc.'s Profile

patented technology to grow and expand adult Stem Cells Adult stem cell development company commencing clinical trials applicable to estimated $30 billion degenerative disease market place

Pluristem Life Systems, Inc. (OTCBB: PLRS) biotechnology company is dedicated to the commercialization of allogeniec cell therapy products for the treatment of severe blood, cardiovascular and autoimmune disorders. The first product planned by the company is dedicated to resolving the global shortfall of matched tissue for bone marrow transplantation by improving the engraftment of umbilical cord blood (UCB). The Company owns GMP early stage facilities and an animal house to conduct research, development and manufacturing of its products.

Pluristem has discovered and patented a process to grow and expand Adult Mesenchymal and Hematopoietic Stem Cells (MCS, HSC). Cell expansion is executed in an environment that mimics natures microstructure of bone marrow and does not include the supplemented growth factors of cytokines. It is for this reason that Pluristem's Technology is to the best of our knowledge the most efficient and safe way to grow Mesenchymal and Hematopoietc stem cells on a production scale for cell therapy products. The first product targets a critical global shortfall of matched tissue for bone marrow transplantation (BMT).

Pluristem’s pipeline of products begins as adherent stromal cells (ASCs) that are derived from the human placenta, an organ that has traditionally been considered medical waste after childbirth and a non-embryonic, non-controversial source of cells. Pluristem’s placental-derived ASCs are then grown in a unique and proprietary three-dimensional (3D) microenvironment, termed the Pluristem PluriX™ 3D bioreactor, without the addition of growth factors or other adulterants. The ASCs derived from this process are called PLacental eXpanded or PLX cells. Pluristem believes these cells' efficacy may be related to the secretion of cytokines or other potent immune modulators. Furthermore, these PLX cells are immune-privileged and possess immunomodulatory properties, thus protecting the recipient from immunological reactions that often accompany transplantations. The PLX cells are stored “ready to use” with no histocompatibility matching required.

Pluristem is an American public company that employs 29 talented, experienced individuals including four PhDs and an MD. The Company has an office in Colorado with headquarters housing its research and development and FDA good manufacturing practices (GMP)-approved facilities in Haifa, Israel.










Last changed at 07-Feb-2011 02:43PM by emit

Management & Directors

  • Zami Aberman

    President & CEO

    Mr. Aberman joined Pluristem in September 2005 and changed the Company’s strategy towards cellular therapeutics. Mr. Aberman has 20 years of experience in marketing and management in the high technology industry. He has held Chief Executive and Chairman positions in Israel, the USA, Europe, Japan and Korea. He has operated within high-tech global companies in the fields of automatic optical inspection, network security, video over IP, software, chip design and robotics. Continued... on copr-website.

  • Yaky Yanay,

    VP Finance & CFO

    Prior to joining Pluristem, Mr. Yanay was the Chief Financial Officer of Elbit Vision System Ltd. (EVSNF.OB), a company engaged in automatic optical inspection. He has extensive experience in the financing and management of technology companies. He played a major role in planning and executing a turn-around plan for Elbit Vision System, including the completion of three acquisitions and the raising of more than $20 million, resulting in a tripling of the company’s revenues and attaining profitability. Mr. Yanay began his financial career at Ernst &Young Israel in 1999, where he served as a manager of audit groups for the technology sector. He joined Ernst &Young’s financial team after serving in the Israeli Ministry of Foreign Affairs since 1993.

    Mr. Yanay holds a bachelor’s degree with honor in business administration and accounting from the College of Management Studies in Rishon Le Zion, Israel and is a Certified Public Accountant in Israel.

  • William R. Prather RPh, MD,

    Senior VP Corporate Development

    William R. Prather RPh, MD, is a Registered Pharmacist as well as a Board Certified Internist and Geriatrician. Dr. Prather received his BS in Pharmacy (1970) and medical degree (1973) from the University of Missouri. He practiced internal medicine in the Kansas City, MO and Vail, CO areas until leaving Internal Medicine in 1987 to pursue a Fellowship in Geriatric Medicine at Harvard University. He completed this Fellowship in 1989.

    In 1992 Dr. Prather left the practice of medicine to pursue a career in the financial industry where he has held Senior Healthcare research positions for a variety of investment banks . Dr. Prather co-founded Panacos, Inc. (NASDAQ:PANC), a public pharmaceutical company. Additionally, he has been on the Boards of several public and private companies, including Boston Biomedica Inc. (a public medical diagnostics company), PriMed (a private medical device company), MdBio (a Maryland healthcare venture firm), and sat on the Advisory Board of MDS Capital Management, (a Canadian venture firm).

  • Frank C. Carlucci

    Business Strategy Advisory Board

    Mr. Carlucci has been a Managing Director of Carlyle since 1989, Chairman since 1993 and Chairman Emeritus since January 2003. Mr. Carlucci was Secretary of Defense from November 1987 through January 1989, following his service as Assistant to the President for National Security Affairs under President Reagan. Before serving in these positions, Mr. Carlucci was Chairman and CEO of Sears World Trade, a business he joined in 1983. Mr. Carlucci preceded his affiliation with Sears World Trade, Inc. with a career in government service, which included Deputy Secretary of Defense (1980-82), Deputy Director of Central Intelligence (1978-80), Ambassador to Portugal (1975-78), Under Secretary of Health Education and Welfare (1973-75), Deputy Director of OMB (1970-72), and Director of the Office of Economic Opportunity (1969). Mr. Carlucci was a Foreign Service Officer from 1956 to 1980 and he served as an officer in the U.S. Navy from 1952 to 1954.

    Mr. Carlucci is Chairman Emeritus of Nortel Networks and the US-Taiwan Business Council and the Chairman of the Neurogen Corporation Board of Directors. Additionally, Mr. Carlucci serves as a member on the following corporate boards: SunResorts, Ltd., N.V.; Texas Biotechnology Corporation and United Defense L.P.

  • Philip S. Schein, M.D

    Business Strategy Advisory Board

    Dr. Philip Schein is widely regarded as a leading international authority in the treatment of cancer. He currently serves as a Visiting Professor in Cancer Pharmacology, Oxford University, and President of The Schein Group, which provides consultative services to the pharmaceutical industry. He is a former President of the American Society of Clinical Oncology, Chairman of the FDA Oncology Drugs Advisory Committee and a member of the National Cancer Advisory Board. His prior appointments were at the National Cancer Institute, Bethesda, Maryland where he served as Senior Investigator and Head of the Clinical Pharmacology Section of the Medicine Branch and at Georgetown University School of Medicine in Washington, DC, as Professor of Medicine and Pharmacology and Scientific Director of the Vincent T. Lombardi Cancer Research Center. He has also served as Vice President of Worldwide Clinical Research and Development, and Director of the Laboratory of Molecular Oncology, SmithKline & French Laboratories, where he had responsibility for all SK&F clinical research and development activities. In 1987 he founded US Bioscience, a pharmaceutical company focused in the field of oncology, where he served as Chairman and CEO of U.S. Bioscience and took three products, Ethyol, Neutrexin and Hexalen, through development and regulatory approval in the US, Europe, Canada and other countries.

Broker Fact Sheet

  • PSTI Broker Fact Sheet
    Thu Mar 29, 2019
    Fact sheet details
Pluristem Life Systems, Inc.
Symbol
PSTI
Exchange
NAZ
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26.32M
Industry
Technology & Medical
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