Resverlogix Corp.

Welcome To The Resverlogix HUB On AGORACOM Edit this title from the Fast Facts Section
in response to chicagoest's message

Chicagoest,

As far as I know, the only MOA that Resverlogix has disclosed for how RVX-208 may mitigate neurodegenerative diseases such as Alzheimer's is related to the ability of RVX-208 to elevate apoAI and HDL. However, there may be a lot more going on behind the scenes that would offer additional MOAs. So yes, it is possible that RVX-208 could improve the function of Verubecestat, but it's hard to guess not knowing more about how RVX-208 works in the brain. RVX does have a neurodegenerative clinical advisory board, and a substudy of BETonMACE is related to some memory/Alzheimer's readouts.....so clearly RVX is not giving up on Alzheimer's yet.

http://www.prnewswire.com/news-releases/resverlogix-assert-trial-data-illustrates-potential-for-rvx-208-in-alzheimers-disease-114560869.html

https://www.resverlogix.com/upload/latest_news/81/01/2008-11-10_alzheimers_program_final.pdf

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BearDownAZ
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Resverlogix Corp.
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