Critical Outcome Technologies Inc

Welcome To The Critical Outcome Technologies Inc HUB On AGORACOM Our disease Targets > Small cell lung cancer, Multiple sclerosis, HIV Integrase, Colorectal cancer & Adult acute leukemia

over 7 years ago

in response to hoov's message

Phase 1 clinical trials are designed to test the safety and tolerance of the treatment. This is the fastest advance to the fourth dosage cohort for a cancer treatment that I have ever seen.

In order to escalate the dose, an independent safety committee must review detailed data about the effect of the treatment on the subjects. As a secondary measure, the effect of the treatment on the cancer will also be monitored.

The P53 gene mutation associated with these gynecological cancers is also seen in many other cancers. If proven safe and effective in this trial, COTI-2 will very likely be rapidly tested in other cancers exhibiting the P53 oncogenetic mutation.

Lar